Platelet Derived Growth Factor

Platelet Derived Growth Factor (PDGF) with Ariessence®

Restore, Repair, and Renew with Ariessence at Skin Secrets

Dr. Greta McLaren

Only your doctor knows for sure.

The future of skincare is regenerative medicine, and at Skin Secrets by Dr. Greta McLaren, we are proud to be at the forefront of this innovation. One of the most exciting breakthroughs is Platelet Derived Growth Factor (PDGF)—a clinically proven protein that works at the cellular level to repair damage, stimulate collagen, and rejuvenate the skin from within.

To deliver these benefits, we offer Ariessence®, an advanced growth factor formulation designed to maximize PDGF’s regenerative power. This next-generation therapy helps smooth fine lines, restore firmness, accelerate post-procedure healing, and improve overall skin tone and texture.

If you’re looking for a science-backed, results-driven solution for anti-aging and skin renewal, PDGF therapy with Ariessence at Skin Secrets is a powerful way to restore, repair, and protect your skin’s natural beauty.

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What is Platelet Derived Growth Factor (PDGF)?

Platelet Derived Growth Factor (PDGF) is a naturally occurring protein found in blood platelets, the cells that help with clotting and tissue repair. When your body experiences an injury, PDGF is released to signal nearby cells to multiply, migrate, and repair damage.

In aesthetics, this same healing mechanism is applied to rejuvenate the skin. By stimulating collagen production, improving blood flow, and encouraging cell turnover, PDGF helps create smoother, firmer, and more radiant skin.

How PDGF Works in the Skin:

  • Cell Regeneration – Promotes fibroblast and smooth muscle cell activity to strengthen skin structure.
  • Collagen & Elastin Production – Boosts the proteins responsible for youthful, elastic skin.
  • Wound Healing – Accelerates skin repair after injury or cosmetic procedures.
  • Angiogenesis – Encourages new blood vessel formation, enhancing nutrient delivery.
  • Synergy with Other Growth Factors – Works in tandem with VEGF, TGF-β, and EGF for comprehensive skin healing.
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@skinsecretsmd ✨ Say goodbye to tired eyes! PDGF (Platelet-Derived Growth Factor) helps rejuvenate under-eye skin by boosting collagen, reducing fine lines, and improving firmness. Brighter, smoother, younger-looking eyes start here. 👁️💉 #EyeRejuvenation #PDGF #SkincareScience #UnderEyeCare ♬ There She Goes - CYRIL & MOONLGHT & The La's

Why PDGF Matters in Aesthetics?

In aesthetics and dermatology, PDGF has moved from being a healing factor to becoming a cosmetic powerhouse. Because it plays a natural role in repairing skin, stimulating collagen, and restoring tissue, PDGF can be harnessed in skincare formulations and treatments to:

  • Minimize fine lines and wrinkles
  • Repair sun-damaged skin
  • Improve recovery after procedures like microneedling or lasers
  • Enhance long-term skin strength and resilience
pdgf-before-and-after
Image credit: ariessence.com

By incorporating PDGF into advanced products such as Ariessence®, Skin Secrets by Dr. Greta McLaren brings medical-grade science into everyday skincare routines—making cellular-level healing accessible for anyone wanting radiant, youthful skin.

Ariessence®: Harnessing the Power of PDGF

Ariessence® is an advanced skincare brand formulated with Platelet Derived Growth Factor to rejuvenate skin at the cellular level. Unlike traditional skincare products that only treat the surface, Ariessence penetrates deeper to stimulate true regenerative healing.

ariessence pure pdgf

Why Choose Ariessence®?

  • Backed by Science – Uses PDGF, a proven protein in regenerative medicine.
  • Professional Grade – Formulated for use in both clinical settings and at-home routines.
  • Amplifies Procedures – Works synergistically with treatments like PRP, lasers, and microneedling.
  • Targets Multiple Concerns – From fine lines to post-treatment healing, Ariessence addresses it all.
  • Safe & Effective – Designed to minimize irritation while maximizing results.
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Pairing Ariessence PDGF with In-Office Treatments

At Skin Secrets, we often combine Ariessence with other aesthetic procedures for enhanced outcomes:

I have been a client of Skin Secrets for over two years. The entire staff is wonderful. I mainly see Janet for my procedures. She is very skilled, intelligent and kind. My skin has improved greatly. Thank you Janet!
Lisa D.
Everyone at Skin Secrets is so professional and caring. Dr. McLaren is very knowledgeable and takes pride in her ability, wants to make sure everything is right. Janet, who is Dr. McLaren assistant is the most helpful person, she will take the time to explain procedures and what to expect, no matter how busy she is. Always has a smile and a super nice personality! I'm so pleased to have found Skin Secrets.
Debbie A.
It’s a pleasure to work with Dr. McLaren. She’s very knowledgeable and gives advice to what will make you look better not what will make her more money. Her whole entire staff is very professional and courteous.
Janet C.
I have had numerous services here. I cannot say enough about the people there and the quality of the services they provide . It is truly an exception when you are treated like family instead of feeling like you’re being put on a conveyor belt like many places today. the staff is amazing especially Janet, who just goes over and beyond. The rest of the staff is incredible. I always feel like I’m visiting with friends. Do give them a try and go find out yourself.
Anne H.

Frequently Asked Questions (FAQs)

  • ariessence® pure PDGF+, is a cosmetic product consisting of proprietary, pure, recombinant, sterile platelet-derived growth factor (PDGF) and a proprietary blend of sterile hyaluronic acid (HA) for topical use designed to improve the appearance of skin. ariessence is not intended to treat, diagnosis or prevent any disease, or affect the structure or function of the human body
  • Accordingly, while ariessence is listed with FDA as cosmetic product (Cosmetic Product Listing Number – 53-171423-311193), like most other cosmetic products, the specific ariessence product has not received, nor does it require approval by FDA
  • While ariessence is not FDA approved, the pure PDGF component of ariessence is also present in four (4) medical therapeutic products that are FDA approved. The pure PDGF in ariessence is exactly the same, and from the same manufacturing line and meets the same exacting standards, as the pure PDGF in the 4 FDA approved products*
The following 4 products are different formulations containing PDGF.  Each has received the highest level of FDA approval, which requires the most stringent FDA review and approval processes; these processes require pre-clinical and clinical trials providing proof of the safety and effectiveness of the product.
Not necessarily. Although there are certain FDA-approved products that contain PDGF (see above), these are drug-device combination products and/or are intended for use in the treatment, cure, mitigation, or prevention of disease or intended to affect the structure or functions of the body.

Over 5 million people are believed to have been treated with PDGF over the past 15 years.

A kit of Ariessence includes 5 syringes of PDGF-BB (ingredients: Water, Sodium Acetate, sh-Polypeptide-59 Dimer aka PDGF-BB) and one vial of sterile, uncrosslinked, high- and low-molecular weight HA (ingredients: Water, Sodium Acetate, Hyaluronic Acid.

Yes. PDGF is the most well studied tissue growth factor in regenerative medicine. There are literally thousands of peer-reviewed published studies on PDGF encompassing over 100 clinical trials involving the use of PDGF.

No. The pure PDGF in ariessence is made via cutting edge recombinant technology, a highly regulated sterile manufacturing process resulting in pharmaceutical grade PDGF with no human components. It is not derived from any human tissue or cells. Every lot of PDGF meets exacting standards established during the FDA approval process for purity, potency and sterility. This process is similar to how many FDA approved biologic drugs are made today.

Why Choose Skin Secrets by Dr. Greta McLaren?

Dr. Greta McLaren

Dr. Greta McLaren, is a board-certified physician and a leader in cosmetic and anti-aging medicine. She earned her medical degree at the prestigious University of Colorado School of Medicine, where she later founded the school’s first cosmetic anti-aging clinic and served as an Assistant Clinical Professor.

When it comes to regenerative skincare, expertise matters. Dr. Greta McLaren is known for her personalized, science-backed aesthetic treatments that prioritize both safety and results.

At Skin Secrets, you’ll receive:

  • Customized treatment plans tailored to your skin’s needs
  • Access to Ariessence PDGF formulations and advanced procedures
  • Professional guidance for both in-office and at-home care
  • A compassionate, patient-centered approach to beauty and wellness

Cape Coral, Florida's Top Medical Spa, and Anti-Aging Clinic

Your skin deserves more than surface-level care—it deserves cellular-level renewal that works with your body’s natural healing process. With Platelet Derived Growth Factor (PDGF), you’re not just treating the signs of aging—you’re addressing the root cause of skin decline by stimulating true regeneration. 

Call Skin Secrets today at 239-800-SKIN (7546) or message us online to schedule your consultation and learn how Ariessence PDGF therapy can help you achieve radiant, youthful skin.

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"Only your doctor knows for sure."

- Dr. Greta McLaren

  • She was one of the first physicians to offer Botox and Laser treatments in the Denver area.
  • She is a laser Surgeon and aesthetic medicine specialist.
  • Member of the American Society of Laser Medicine and Surgery, and American Society for Photodynamic Therapy.
  • A Denver native and an assistant clinical professor for the prestigious University of Colorado.